Amanda Hernan, PhD
Research Scientist- Attention
- Cognition
- Early Life Seizures
- Epilepsy
- Prefrontal Cortex
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Network鈥恇ased analysis predicts interacting genetic modifiers from a meta鈥恗apping study of spike鈥搘ave discharge in mice; Genes, Brain and Behavior; (2024).
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Mechanisms for Cognitive Impairment in Epilepsy: Moving Beyond Seizures; Frontiers in Neurology; (2022).
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Differential regulation of gene expression pathways with dexamethasone and ACTH after early life seizures; bioRxiv; (2022).
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Fine Spike Timing in Hippocampal-Prefrontal Ensembles Predicts Poor Encoding and Underlies Behavioral Performance in Healthy and Malformed Brains; Cerebral Cortex; (2021).
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Distributed dynamic coding for spatial working memory in hippocampal-prefrontal networks; bioRxiv; (2019).
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Environmental enrichment normalizes hippocampal timing coding in a malformed hippocampus; PLoS ONE; (2018).
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Environmental Enrichment Normalizes Hippocampal Timing Coding in a Malformed Hippocampus; bioRxiv; (2017).
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Methodological standards and functional correlates of depth in聽vivo electrophysiological recordings in control rodents. A TASK1-WG3 report of the AES/ILAE Translational Task Force of the ILAE; Epilepsia; (2017).
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ACTH prevents deficits in fear extinction associated with early life seizures; Frontiers in Neurology; (2016).
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Antiepileptic drug treatment strategies in neonatal epilepsy; Progress in Brain Research; (2016).
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Short-range temporal interactions in sleep; Hippocampal spike avalanches support a large milieu of sequential activity including replay; PLoS ONE; (2016).
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Stimulation of glutamate receptors in the ventral tegmental area is necessary for serotonin-2 receptor-induced increases in mesocortical dopamine release; Neuroscience; (2015).
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Alterations in sociability and functional brain connectivity caused by early-life seizures are prevented by bumetanide; Neurobiology of Disease; (2015).
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Attention deficit associated with early life interictal spikes in a rat model is improved with ACTH; PLoS ONE; (2014).
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Focal epileptiform activity in the prefrontal cortex is associated with long-term attention and sociability deficits; Neurobiology of Disease; (2014).
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Altered short-term plasticity in the prefrontal cortex after early life seizures; Neurobiology of Disease; (2013).
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Thrombin facilitates seizures through activation of persistent sodium current; Annals of Neurology; (2012).
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Early-life seizures produce lasting alterations in the structure and function of the prefrontal cortex; Epilepsy and Behavior; (2011).